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Training the Next Generation of Talent

New Graduate Internship Program Builds Bridges Between DOE JGI, UC Merced Days after presenting the results of his summer research at the U.S. Department of Energy Joint Genome Institute (DOE JGI), a DOE Office of Science user facility, Keedrian Olmstead was back on campus at the University of California, Merced to start orientation as a… [Read More]

Going deep to find drought-tolerant genes in Brachy

Many unannotated genes identified through sequencing multiple lines of the model grass. The Science Researchers used deep sequencing to look at whole-genome sequence variation in seven lines of the model grass Brachypodium distachyon and found previously unannotated genes. They also looked at genome-wide gene expression under drought-stress conditions. The Impact Hundreds of genes not present… [Read More]

nucleotid.es genome assembly tool in GenomeWeb

“Nucleotid.es, a publicly available repository developed by a researcher at the Joint Genome Institute, aims to provide a comprehensive list of genome assemblers and associated benchmarks that will help researchers in the genomics community select and use the most appropriate assembly tools for their sequencing projects.” Full story on GenomeWeb. (Note: Free registration may be… [Read More]

Elucidating Extremophilic “Microbial Dark Matter”

Metagenomics and single-cell genomics are providing the first substantial genomic data on uncultured microbes in extreme environments. The Science: Genomes from novel lineages of bacteria and archaea in extreme environments have become accessible through techniques such as metagenomics and single-cell genomics. The Impact: Applying single-cell genomics and metagenomics toward uncultivated microbes in extreme environments has… [Read More]

Decoding Virus-Host Interactions in the Oxygen-Starved Ocean

For multicellular life—plants and animals—to thrive in the oceans, there must be enough dissolved oxygen in the water. In certain coastal areas, extreme oxygen-starvation produces “dead zones” that decimate marine fisheries and destroy food web structure. As dissolved oxygen levels decline, energy is increasingly diverted away from multicellular life into microbial community metabolism resulting in… [Read More]

Far-Red Light Makes Far-Reaching Algal Changes

How a cyanobacterial strain adapts to boost photosynthesis efficiency under various light conditions. The Science: Researchers sequence the genome of a cyanobacterial strain isolated from hot springs near Yellowstone National Park and conduct gene expression and metabolic studies to understand how it adapts to utilize far-red light to photosynthesize. The Impact: Understanding how cyanobacteria utilize… [Read More]

Comparing Genomes/Lifestyles of Freshwater Bacteria

Single-cell genomics sheds light on nutrient and carbon cycling in Actinobacteria. The Science: Researchers assembled and compared draft genomes of acI Actinobacteria from single cells collected in four freshwater lakes in the United States and Europe. The Impact: The single cells collected represented three different acI tribes of Actinobacteria, allowing researchers to learn more about… [Read More]

Understanding Aureobasidium’s Adaptability

Differences between genome sequences warrant fungal reclassifications. The Science: Researchers sequenced four samples of Aureobasidium fungi from various regions of the world to learn more about their potential biotechnological applications. The Impact: Comparative genomic analyses reveal genes that make the fungi capable of adapting to a wide range of environments and stresses, which can be… [Read More]

How yeast formations got started

Comparative analyses reveal gene family conserved across multiple yeast lineages. The Science: Researchers conducted a comparative analysis of nearly 60 fungal genomes to determine the genetic traits that enabled the convergent evolution of yeasts. The Impact: The analyses suggest that a conserved zing-finger transcription factor family allowed yeasts to become the dominant form in multiple… [Read More]