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April 6, 2017

Discovered: Novel Group of Giant Viruses

Giant virus acquiring genes from different eukaryotic host cells. (Ella Maru studio, http://www.scientific-illustrations.com/)Giant viruses appear to have evolved from smaller viruses (not from cells) based on presence of nearly complete set of translation-related genes. Viruses have a ubiquitous presence in the world. Their population is estimated to be 1031, 10 times greater than the nonillion (1030) of microbes on the planet—a figure that surpasses the number of… [Read More]

February 27, 2017

Revealing Aspergillus Diversity for Industrial Applications

Comparative growth of aspergilli. (Ad Wiebenga & Ronald de Vries, Westerdijk Fungal Biodiversity Institute, Utrecht, The Netherlands)Comparative analysis of Aspergillus species provides genus-wide view of fungal diversity In the world of fungi, Aspergillus is an industrial superstar. Aspergillus niger, for example, has been used for decades to produce citric acid—a compound frequently added to foods and pharmaceuticals —through fermentation at an industrial scale. Other species in this genus play critical roles… [Read More]

January 19, 2017

Seeking Structure With Metagenome Sequences

From sample to structure. Top: Researchers gathering samples from Great Boiling Spring in Nevada. Left: a snapshot of aligned metagenomic sequences. Each row is a different sequence (the different colors are the different amino acid groups). Each position (or column) is compared to all other positions to detect patterns of co-evolution. Bottom: the strength of the top co-evolving residues is shown as blue dots, these are also shown as colored lines on the structure above. The goal is to make a structure that makes as many of these contacts as possible. Right: a cartoon of the protein structure predicted. The protein domain shown is from Pfam DUF3794, this domain is part of a Spore coat assembly protein SafA. (Image of Great Boiling Spring by Brian Hedlund, UNLV. Protein structure and composite image by Sergey Ovchinnikov, UW)Metagenomics database helps fill in 10 percent of previously unknown protein structures For proteins, appearance matters. These important molecules largely form a cell’s structures and carry out its functions: proteins control growth and influence mobility, serve as catalysts, and transport or store other molecules. Comprised of long amino acid chains, the one-dimensional amino acid sequence… [Read More]

January 16, 2017

Tracking Antarctic Adaptations in Diatoms

Scanning electron micrograph of two cells of Fragilariopsis cylindrus. Shown are two silica shells (Frustules) in valve view. Magnification: 15,000X; scale bar: 5 μm (Image credit: Gerhard S. Dieckmann)Comparative genome analysis provides clues on how climate change might impact evolutionary adaptation limits Diatoms are a common type of photosynthetic microorganism, found in many environments from marine to soil; in the oceans, they are responsible for more than a third of the global ocean carbon captured during photosynthesis. This leads to a significant amount… [Read More]

January 10, 2017

Industrial Biotechnology Leader to Assume the Helm of the DOE Joint Genome Institute

Nigel MounceyAfter a 9-month national search, Nigel Mouncey, currently Research and Development Director for Bioengineering and Bioprocessing at Dow AgroSciences LLC, has been selected as the Director of the U.S. Department of Energy Joint Genome Institute (DOE JGI), a DOE Office of Science User Facility. “Nigel brings the perfect set of scientific and management skills as… [Read More]

November 17, 2016

Engineering a More Efficient System for Harnessing Carbon Dioxide

A MPI video featuring study senior author Tobias Erb discussing this project may be viewed at http://bit.ly/ErbCETCH.Despite the vast diversity of organisms on the planet that express enzymes for the conversion of carbon dioxide into such organic compounds as sugars – as plants do through photosynthesis – the efforts to harness these capabilities to transform CO2 into high-value products such as biofuel and renewable chemicals have met with limited success. While… [Read More]

November 2, 2016

2017 DOE Joint Genome Institute Community Science Program Allocations Announced

John Cushman of the University of Nevada seeks to establish the common or crystalline ice plant (Mesembryanthemum crystallinum L.) as a DOE JGI Flagship Genome species. (Image by Krzysztof Ziarnek, Kenraiz CC BY-SA 4.0 Wikipedia)Portfolio additions build upon contributions in sustainable biofuels, plant microbiomes and biogeochemistry. From deep within the Earth to the upper atmosphere, the organisms and ecosystems highlighted in the 37 projects selected for the 2017 Community Science Program (CSP) of the U.S. Department of Energy Joint Genome Institute (DOE JGI), a DOE Office of Science User… [Read More]

September 7, 2016

How Fungi Help Trees Tolerate Drought

The crosscut shows the fungal tissues - the fungal mantle around the root tip and the the fungal network of tendrils that penetrates the root of plants, or Hartig Net, between Pinus sylvestris plant root cells - in green. (Image by Maira de Freitas Pereira, INRA Nancy.)Genome of world’s most common fungal symbiont sheds light on drought resistance role The mutualistic relationship between tree roots and ectomycorrhizal (ECM) fungi has been shaping forest ecosystems since their inception. ECM fungi are key players supporting the growth, health and stress tolerance of forest trees globally, such as oak, pine, spruce, birch and beech,… [Read More]

September 6, 2016

10 New Projects to be Supported Under Joint DOE User Facility Initiative

This diagram from Petr Baldrian’s proposal shows the seasonal differences in the carbon cycle processes in the temperate and boreal coniferous forests. During vegetation seasons, depicted by September on the left, photosynthesis products are allocated to soil via tree roots. When photosynthesis stops in winter, depicted by March on the right, decomposition is the most important carbon cycle process. (Image courtesy of Petr Baldrian)The U.S. Department of Energy Joint Genome Institute (DOE JGI) and the Environmental Molecular Sciences Laboratory (EMSL) have accepted 10 projects submitted during the 2017 call for proposals for their joint “Facilities Integrating Collaborations for User Science” (FICUS) initiative. These new research projects all involve collaboration between two user facilities that are stewarded by the DOE Office… [Read More]

August 17, 2016

Unveiled: Earth’s Viral Diversity

virome-graphic_art-by-Z-Rostomian-LBNLEnvironmental datasets help researchers double the number of microbial phyla known to be infected by viruses. The number of microbes in, on, and around the planet – on the order of a nonillion, or 1030 – is estimated to outnumber the stars in the Milky Way. Microbes are known to play crucial roles in regulating… [Read More]
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