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September 1, 2005

DOE JGI Releases Latest Version of IMG

WALNUT CREEK, CA–An enhanced version of the Integrated Microbial Genomes (IMG) data management system of the U.S. Department of Energy (DOE) Joint Genome Institute (DOE JGI) has been made available to the public. The new version, IMG 1.2, contains 270 additional public genomes and nine (four finished, five draft) new JGI genomes, bringing the total of genomes in IMG to 618 (318 bacterial, 25 archaeal, 15 eukaryotic, 260 bacterial phage), 40 of which are finished and 80 of which are draft genomes sequenced by DOE JGI.

IMG 1.2 enables users to add annotations to IMG as well as to save the results of their analysis of organisms and genes.  IMG 1.2 also features enhanced comparative analysis capabilities, including VISTA exploration of sequence conservation for selected organisms and KEGG pathway and COG category profiles across all organisms.

Since its initial release in March 2005, IMG has gained increasing recognition in the scientific community. “IMG is invaluable for comparative genomic analyses,” said Mark A. Schell, professor in the Department of Microbiology and Plant Pathology at the University of Georgia. “My laboratory uses it all the time and I will use it in the classes I teach this fall.”

Responding to the growing interest in the community, IMG is developing tools to facilitate use of the system. Through the sponsorship of the DOE Office of Science Laboratory Science Teacher’s Professional Development program (LSTPD), Karen Kelly, a biology teacher from local Clayton Valley High School, spent the summer at the JGI Production Genomics Facility, designing an IMG training workshop for teachers and students.

“They will experience up-close and personal lessons from the researchers on how JGI tackles microbial genomes and how scientific value is added from comparative analyses,” Kelly said.  “From this population, JGI hopes to harness a new generation of intern bioinformaticists that will help advance IMG’s annotation goals.”

IMG, accessible to the public at http://img.archive.jgi.doe.gov/, is the result of a collaboration between the DOE JGI and Lawrence Berkeley National Laboratory’s Biological Data Management and Technology Center (BDMTC).

IMG continues to be updated on a quarterly basis with new public and JGI genomes. The next update is scheduled for December 1st, 2005.

The DOE Joint Genome Institute, supported primarily by the DOE Office of Science, is among the world leaders in whole-genome sequencing projects devoted to microbes and microbial communities, model system vertebrates, aquatic organisms, and plants. Established in 1997, DOE JGI now unites the expertise of four national laboratories, Lawrence Berkeley, Lawrence Livermore, Los Alamos, and Oak Ridge, along with the Stanford Human Genome Center to advance the frontiers of genome sequencing and related biology.

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The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science User Facility at Lawrence Berkeley National Laboratory, is committed to advancing genomics in support of DOE missions related to clean energy generation and environmental characterization and cleanup. JGI provides integrated high-throughput sequencing and computational analysis that enable systems-based scientific approaches to these challenges. Follow @jgi on Twitter.

DOE’s Office of Science is the largest supporter of basic research in the physical sciences in the United States, and is working to address some of the most pressing challenges of our time. For more information, please visit science.energy.gov.

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