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Bioinformatics challenges for metagenomic analyses

There are more microbes in, on and around the planet than there are stars in the sky. However, the vast majority of these microorganisms have not yet been studied, in part because many of them do not thrive when moved out of their natural environment. A spoonful of soil contains a complex and diverse microbial… [Read More]

Soil biocrust microbial genome

One of the DOE JGI’s 2011 Community Sequencing Program projects involves studying biological soil crusts to understand their role in the global carbon cycle. Found in arid lands which make up nearly half of the planet’s total land mass, communities of lichens, mosses and cyanobacteria use soil particles to form biocrusts less than half an… [Read More]

Toward a Better Understanding of Soil-Microbe Interactions

In the August 2011 issue of the Journal of Bacteriology, a team of researchers led by DOE JGI’s Patrick Chain at Los Alamos National Laboratory focused on a microbe that can help or harm as the case may be. Ochrobactrum anthropi thrives in a variety of habitats including polluted soil, plants and even higher mammals…. [Read More]

Daphnia pulex project on LANL News Center

The journal Science has published the recently completed 200-million base-pair genome sequence of the water flea, Daphnia pulex. The DNA code is the largest number of genes ever recorded for a multicellular animal (more than in the human genome!), and one-third are of unknown function. Chris Detter of the Laboratory’s Genome Science and leader of… [Read More]

JGI researchers on Caliper’s Scientific Advisory Board

Caliper Life Sciences Inc., a Hopkinton-based provider of tools and services for drug discovery and life sciences research, recently formed a scientific advisory board to guide its efforts in automated sample preparation for next-generation and third-generation sequencing platforms. Read more at Metro West Daily News.  [Read More]

Genome Project Standards paper covered by GenomeWeb

With sequencing speed increasing and cost decreasing, some have estimated that public databases will house 12,000 draft genomes by 2012. But because the quality and completion of these genomes varies dramatically, the authors suggest new standards are needed to classify draft and finished genomes — and everything in between. “Exponential leaps in raw sequencing capability… [Read More]

“Establishing standard definitions for genome sequences” on Science Codex

As the proverbial “fire hose of data” becomes a Niagara torrent, with conservative estimates of 12,000 draft genomes hitting the public databases by 2012, researchers may be surprised to find that these datasets describe genomes that are not complete. Recognizing the problem, a group of researchers from several sequencing centers, including the DOE Joint Genome… [Read More]

“Joint Announcement sets Six Genome Sequence Standards”

“Standards are a major issue to be tackled in genomics right now,” says Patrick Chain from Los Alamos National Laboratory (LANL), New Mexico, USA and joint first author. “These proposals are guideposts meant to inform users and generators.” A range of next-generation sequencing technologies, increasingly deployed in research, generate massive amounts of data in any… [Read More]

Need for standard definitions covered by PhysOrg

As the proverbial “fire hose of data” becomes a Niagara torrent, with conservative estimates of 12,000 draft genomes hitting the public databases by 2012, researchers may be surprised to find that these datasets describe genomes that are not complete. Recognizing the problem, a group of researchers from several sequencing centers, including the DOE Joint Genome… [Read More]