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Content Tagged "single cell genomics"

Microbial genomes help propose phylum name

Metagenomicsand single-cell genomics are tools helping researchers learn more about the “biological dark matter” that has not been cultivated and studied in the laboratory. In an article published May 14, 2013 in Nature Communications. [Read More]

Deepwater Horizon oil spill cleanup microbes project in Examiner.com

The first research effort reported in an article published online June 21, 2012, in the ISME Journal involved samples taken immediately after the Deepwater Horizon spill began and during the ensuing clean up efforts.The researchers found that a variety of microbes consumed parts of the oil spill selectively. Each group of microbes specifically targeted one group of… [Read More]

Deepwater Horizon cleanup microbes project in Oil and GasOnline

To learn more about the microbial community’s response to the oil spill, researchers led by Berkeley Lab senior scientist Janet Jansson availed themselves of the expertise and resources at two of the Lab’s national user facilities, the U.S. Department of Energy Joint Genome Institute (DOE JGI) and the Advanced Light Source (ALS). The work done… [Read More]

“JGI Looking Beyond Whole Genomes” – GenomeWeb’s In Sequence

The Department of Energy’s Joint Genome Institute has already churned out over 40 trillion bases of sequence data this year, using a variety of next-generation sequencers for applications including de novo whole genome sequencing, RNA-seq, ChIP-seq, methylation sequencing, and even some single cell sequencing.While the majority of its work is currently in whole genome sequencing,… [Read More]

Tanja Woyke: Genome Technology 2011 Young Investigator

What inspired Tanja Woyke to pursue her current area of focus is also what makes it possible: single-cell genomic technology. “It allows one to sequence the genome of one individual microbial cell by amplifying its genome a billion-fold using a process called multiple displacement amplification,” she says. “I find this quite fascinating. Such an approach… [Read More]

UV treatments for contaminated MDA reagents

  Single cell genomicsis a method used by researchers to get around the research roadblock thrown up by the need for large amounts of microbial DNA in order to do traditional sequencing techniques. In this process, a single cell isolated from an environmental sample is amplified to make millions of copies of the microbial genome… [Read More]

Dark ocean project in Climate Action

To understand the world’s climate, we must understand how the 70% of the Earths surface that is covered with water behaves. Very little is known about the processes below 200m, or the area where photosynthesis is not possible due to the lack of light penetration. Scientists from the U.S. Department of Energy Joint Genome Institute… [Read More]

Single cell sequencing in Genome Technology

Using a single-cell approach developed by Ramunas Stepanauskas at the Bigelow Laboratory for Ocean Sciences in West Boothbay Harbor, Maine, a group of researchers aims to sequence 60 new marine bacterio-plankton in conjunction with the US Department of Energy’s Joint Genome Institute. That way, there will be better reference genomes available for researchers studying marine… [Read More]

DOE JGI as ‘Genomics Foundry’ in GenomeWeb

The Joint Genome Institute plans to transition from a sequencing center to a “genomic foundry” — a one-stop shop for large-scale functional annotation, single-cell genomics and transcriptomics, high-throughput custom sample prep, and analysis expertise, among other proposed services, said Eddy Rubin at JGI’s sixth annual User Meeting in Walnut Creek, Calif. Ultimately, Rubin said, he… [Read More]