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Tanja Woyke: Genome Technology 2011 Young Investigator

What inspired Tanja Woyke to pursue her current area of focus is also what makes it possible: single-cell genomic technology. “It allows one to sequence the genome of one individual microbial cell by amplifying its genome a billion-fold using a process called multiple displacement amplification,” she says. “I find this quite fascinating. Such an approach… [Read More]

UV treatments for contaminated MDA reagents

  Single cell genomicsis a method used by researchers to get around the research roadblock thrown up by the need for large amounts of microbial DNA in order to do traditional sequencing techniques. In this process, a single cell isolated from an environmental sample is amplified to make millions of copies of the microbial genome… [Read More]

Dark ocean project in Climate Action

To understand the world’s climate, we must understand how the 70% of the Earths surface that is covered with water behaves. Very little is known about the processes below 200m, or the area where photosynthesis is not possible due to the lack of light penetration. Scientists from the U.S. Department of Energy Joint Genome Institute… [Read More]

Single cell sequencing in Genome Technology

Using a single-cell approach developed by Ramunas Stepanauskas at the Bigelow Laboratory for Ocean Sciences in West Boothbay Harbor, Maine, a group of researchers aims to sequence 60 new marine bacterio-plankton in conjunction with the US Department of Energy’s Joint Genome Institute. That way, there will be better reference genomes available for researchers studying marine… [Read More]

Finding cellulases in sediment from a paper mill

During the DOE JGI User Meeting held in Walnut Creek, Calif. from March 22-24, 2011, collaborator Daniel Distel noted that more than 20 enzymes are needed to break down cellulose. To assist in identifying novel cellulose degraders and thus improve cellulosic biofuel production processes, a team of DOE JGI researchers including Microbial Program head TanjaWoyke… [Read More]

Cow rumen metagenome study in This Week in Science

Identification of additional enzymes that can degrade cellulose efficiently should help in the development of biofuels on an industrial scale. Uncultured microorganisms living in cow rumen are highly effective at degrading plant cell walls. Hess et al. used metagenomics and single-genome sequencing to assemble draft genomes from microbes adhering to rumen-incubated switchgrass to identify nearly… [Read More]