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January 27, 2011

Cow rumen metagenome study on PhysOrg

Bovines are thought to have first appeared on the landscape millions of years ago and were domesticated by humans about 10,000 years ago. Rumen microbes evolved to produce molecular machines in the form of enzymes able to efficiently deconstruct plant cell wall polysaccharides such as cellulose and hemicellulose into their constituent small sugar molecules. Another… [Read More]

January 27, 2011

Cow rumen metagenome study on ScienceBlog

The researchers also were able to assemble the genomes of 15 previously “uncultured” (never before grown in a lab) microbes, said Hess, who is first author on the new study. Several techniques, including sequencing the genomes of individual cells and comparing those to the assembled genomes, validated this approach, he said. Read more on ScienceBlog. [Read More]

January 27, 2011

Cow rumen metagenome study on redOrbit

In the new study, the researchers focused on switchgrass, a promising biofuels crop. After incubating the switchgrass in the rumen for 72 hours, researchers conducted a genomic analysis of all of the microbes that adhered to switchgrass. This “metagenomic” approach, led by Edward Rubin, of the DOE Joint Genome Institute and the Lawrence Berkeley National… [Read More]

January 27, 2011

Cow rumen metagenome study in This Week in Science

Identification of additional enzymes that can degrade cellulose efficiently should help in the development of biofuels on an industrial scale. Uncultured microorganisms living in cow rumen are highly effective at degrading plant cell walls. Hess et al. used metagenomics and single-genome sequencing to assemble draft genomes from microbes adhering to rumen-incubated switchgrass to identify nearly… [Read More]
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