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March 5, 2010

BNET on PacBio’s first customers

Last week, Pacific BioSciences, which claims it will map a genome in 15 minutes for less than $1000 by 2013, announced several new partnerships which they say will help customers “rapidly and easily adopt” their sequencing technology. That’s big news, because Pacific BioSciences’s customers are ten research institutions, including major players in genetics like The Broad Institute…

March 5, 2010

Naegleria genome project on NPR

Step aside, Dr. Jekyll and Mr. Hyde. Here’s a story about an organism that dramatically transforms itself when it’s under stress. It turns from a lethargic amoeba into a sprightly, two-armed swimmer. This unlikely single-celled creature is named Naegleria gruberi. It lives in the dirt, under the eucalyptus trees, on the University of California, Berkeley…

March 5, 2010

Naegleria genome project on PhysOrg.com

Scientists have now sequenced the genome of a weird, single-celled organism called Naegleria gruberi that is telling biologists about that transition from prokaryotes, which function just fine with all their proteins floating around in a soup, to eukaryotes, which neatly compartmentalize those proteins? The sequence, produced by the Department of Energy Joint Genome Institute (JGI),…

March 5, 2010

Naegleria genome project on ScienceDaily

Naegleria is a common soil amoeba — the sequenced organism was isolated from the mud in a grove of eucalyptus trees on the UC Berkeley campus — that, under stress, quickly grows two flagella, like sperm tails, that it uses to swim around. It has a third identity, a hard cyst, that can persist in…

March 5, 2010

Naegleria genome project on redOrbit

“In a sense, analyzing the Naegleria genome shows us what it would be like to be on this planet more than a billion years ago, and what kind of organisms were around then and what they might have looked like,” said Simon E. Prochnik, a JGI and UC Berkeley bioinformaticist and coauthor of the Cell…

March 5, 2010

Naegleria genome project on EurekAlert

Scientists have now sequenced the genome of a weird, single-celled organism called Naegleria gruberi that is telling biologists about that transition from prokaryotes, which function just fine with all their proteins floating around in a soup, to eukaryotes, which neatly compartmentalize those proteins? The sequence, produced by the Department of Energy Joint Genome Institute (JGI),…

March 4, 2010

MIT Technology Review: JGI to test PacBio’s new sequencer

The company unveiled the instrument to attendees of the Advances in Genome Biology and Technology meeting, a swanky event that has become the place to make a splash in sequencing. With venture funding of $266 million to date and a unique technology capable of reading single DNA molecules in real-time, Pacific Biosciences has been the…

March 4, 2010

Soybean project in GenomeWeb literature reference

A large team comprised of researchers from Purdue University, the US Department of Energy’s Joint Genome Institute, and the US Department of Agriculture’s Agricultural Research Service used whole-genome shotgun sequencing to sequence roughly 85 percent of the 1.1-gigabase soybean, Glycine max, genome. The paper describes how the team integrated the shotgun approach with physical and…

March 4, 2010

JGI researchers on Caliper’s Scientific Advisory Board

Caliper Life Sciences Inc., a Hopkinton-based provider of tools and services for drug discovery and life sciences research, recently formed a scientific advisory board to guide its efforts in automated sample preparation for next-generation and third-generation sequencing platforms. Read more at Metro West Daily News. 

February 25, 2010

JGI to get PacBio machine on Forbes

PacBio’s DNA-sequencing technology generated a huge amount of excitement when it was described in a cover article in Science because it could someday make it possible to sequence an entire genome in minutes for less than $1,000. The first machines now being rolled out are only a step on the way to this goal, and…

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